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Publications

April 17, 2020

Journal of Biological Chemistry

Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015

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March 25, 2020

Science Translational Medicine

Selective inhibition of TGFB1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape

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July 26, 2019

SLAS Discovery

A Sensitive and Selective Immunoassay for the Quantitation of Serum Latent Myostatin after In Vivo Administration of SRK-015, a Selective Inhibitor of Myostatin Activation

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April 1, 2019

Human Molecular Genetics

Specific Inhibition of Myostatin Activation is Beneficial in Mouse Models of SMA Therapy

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February 2, 2018

Scientific Reports

Blocking extracellular activation of myostatin as a strategy for treating muscle wasting

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January 18, 2018

The Embo Journal

Tolloid cleavage activates latent GDF8 by priming the pro-complex for dissociation.

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